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Recombinant 2019-nCoV Nucleocapsid Protein

Recombinant SARS-CoV-2 Nucleocapsid Protein is produced by our E.coli expression system and the target gene encoding Met1-Ala419 is expressed with a 6His tag at the N-terminus.

Description

Reference ESCIT266
Size 500ug
Molecular Weight 49.4kDa
Purity >95% by SDS-PAGE.
Endotoxin
Biological Activity Immobilized 2019-nCoV Nucleocapsid Protein-His(Cat#DRA31)at 2μg/ml (100μl/well) can bind 2019-nCoV NP Antibody (6G9)(Cat#DA027). The ED50 of 2019-nCoV NP Antibody (6G9)(Cat#DA027) is 5-30 ng/ml.

Other names: 2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein

 

Redissolve:

 

Storage: Reconstituted protein solution should be stored at ≤ -20°C.

 

Shipping Condition: Dry ice pack.

 

Background: Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral rESCIlication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.