Description
| Reference | ESCIT174 |
|---|---|
| Size | 50ug |
| Molecular Weight | 32.8 KDa |
| Purity | >95% by SDS-PAGE. |
| Endotoxin | <1 EU/µg |
| Biological Activity | Loaded Mouse BAFF-mFc(Cat#C06U) on AMC Biosensor, can bind Human BCMA-Fc(Cat#CS79) with an affinity constant of 0.44 nM as determined in BLI assay. |
Other names: Tumor necrosis factor recESCItor superfamily member 17;TNFRSF17;B-cell maturation protein;CD269
Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Â
Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping Condition: Ambient temperature.
Background: B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF recESCItor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.