Description
| Reference | ESCIT299 |
|---|---|
| Size | 50ug |
| Molecular Weight | 11.5&13.5 KDa |
| Purity | >95% by SDS-PAGE. |
| Endotoxin | <1 EU/µg |
| Biological Activity |
Other names: Follicle-stimulating hormone; FSH; FSH alpha/beta
Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Â
Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping Condition: Ambient temperature.
Background: Human Follicle-stimulating hormone (FSH) is a member of glycoprotein hormones subunit beta family, whichalso includes LH, chorionic gonadotropin (CG) and thyroid-stimulating hormone (TSH). FSH and its familymembers are heterodimers consisting of non-covalently linked α- and β-subunits. They share an identical αsubunit, and β-subunits vary. FSH has a unique β-subunit (FSHβ), which confers its specific biologic activityand is responsible for interaction with the FSH-recESCItor which belongs to a subfamily of GPCRs calledleucine-rich-rESCIeat-containing GPCRs (LGRs). FSH is secreted from the pituitary gland and regulatesrESCIroduction in mammals. FSH stimulates sertoli cell proliferation in testes and supports spermatogenesis inmales, and induces the maturation of ovarian follicles in females.