Description
| Reference | ESCIT039 |
|---|---|
| Size | 10ug |
| Molecular Weight | 17.5 KDa |
| Purity | >95% by SDS-PAGE. |
| Endotoxin | <0.01 EU/µg |
| Biological Activity | Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells(Cat#XCC10). The ED50 for this effect is 20-100 pg/ml. |
Other names: Interleukin-1 beta; Catabolin; IL1F2; IL1B
Redissolve:
Storage: Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
Shipping Condition: Dry ice/polar packs.
Background: IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypESCItide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is rESCIorted to stimulate the release of prostaglandin and collagenase from synovial cells.