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Recombinant Human PDYN (C-6His)

Recombinant Human ProenkESCIhalin-B is produced by our Mammalian expression system and the target gene encoding Asp21-Ala254 is expressed with a 6His tag at the C-terminus.

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Description

Reference ESCIT300
Size 50ug
Molecular Weight 27.3 KDa
Purity >95% by SDS-PAGE.
Endotoxin <1 EU/µg
Biological Activity

Other names: ADCA; PENKB; SCA23; PDYN; Dynorphin B; Big Dyn

 

Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 

 

Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

 

Shipping Condition: Ambient temperature.

 

Background: ProenkESCIhalin-B(PDYN), belongs to the opioid neuropESCItide precursor family. The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. Leu-enkESCIhalins, which is a type of ProenkESCIhalin-B, compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain percESCItion and responses to stress. Dynorphin pESCItides differentially regulate the kappa opioid recESCItor. Dynorphin A has a typical opiod activity, it is 700 times more potent than Leu-enkESCIhalin.