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Recombinant Human TGF-beta 2

Recombinant Human Transforming Growth Factor Beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed.

Description

Reference ESCIT195
Size 10ug
Molecular Weight 12.7 KDa
Purity >95% by SDS-PAGE.
Endotoxin <0.01 EU/µg
Biological Activity Immobilized Human TGF-beta 2(Cat#CJ79) at 2μg/ml (100 μl/well)can bind Human TGFBR2-Fc (Cat#CC10).The ED50 of Human TGFBR2-Fc (Cat#CC10) is 1.15 ug/ml.

Other names: Transforming growth factor beta-2; TGFB2; Polyergin; G-TSF; Glioblastoma-derived T-cell suppressor factor; Cetermin; BSC-1 cell growth inhibitor; TGF-beta-2

 

Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 

 

Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

 

Shipping Condition: Ambient temperature.

 

Background: Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dESCIendent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).