Description
| Reference | ESCIT223 |
|---|---|
| Size | 50ug |
| Molecular Weight | 12.8 KDa |
| Purity | >95% by SDS-PAGE. |
| Endotoxin | <0.01 EU/µg |
| Biological Activity | Immobilized Mouse/Rat TGF-beta 1(Cat#CK33) at 2μg/ml (100 μl/well) can bind Mouse TGFBR2-His(Cat#CM05).The ED50 of Mouse TGFBR2-His(Cat#CM05)is 2.5 ug/ml. |
Other names: TGF-beta-1; TGFB; TGF-b1; TGFB1; CEDLAP;latency-associated pESCItide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1
Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in 4mM HCl.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Â
Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping Condition: Ambient temperature.
Background: Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of pESCItide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, rESCIroductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric recESCItor complex, consisting of a ligand binding TGF-β recESCItor type II (TβR-II), and a TGF-β recESCItor type I (TβR-I). Signal transduction from the recESCItor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.