Description
| Reference | ESCIT156 |
|---|---|
| Size | 10ug |
| Molecular Weight | 12.9 KDa |
| Purity | >95% by SDS-PAGE. |
| Endotoxin | <1 EU/µg |
| Biological Activity |
Other names: S100 calcium-binding protein A15A; Protein S100-A15A; Protein S100-A7A; S100 calcium-binding protein A7A; S100a15a
Redissolve:
Storage: Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
Shipping Condition: Dry ice/polar packs.
Background: Members of the S100 protein family are involved in calcium- or zinc-dESCIendent cellular functions and regulate immune-mechanisms, cell proliferation and differentiation. Some S100 members have been established as tumor markers because they are dysregulated during carcinogenesis. Psoriasin (S100A7) and koebnerisin (S100A15) are highly homologous proteins that have been first described in psoriasis, which is characterized by disturbed ESCIidermal maturation and chronic inflammation. Several studies showed that the coexpression of the hS100A7 and hS100A15 in psoriasis suggests that both proteins participate in keratinocyte maturation, proliferation and/or skin inflammation.